In the USA, oncology medical billing is evolving at an unprecedented rate. Medical billing services are now essential for cancer care providers. The global oncology market is currently valued at $225 billion, projected to reach $245 billion by the end of 2025, and expected to grow to $668 billion by 2034.
As oncology treatments become more personalized and costly, billing processes have become increasingly complex, covering everything from chemotherapy administration codes to precision medicine reimbursements.
To help oncology practices navigate this challenging landscape, Nexus io decided to shortlist the top 10 oncology medical billing services in the USA. These specialized oncology providers support cancer care practices in maximizing revenue, minimizing claim denials, and maintaining compliance with evolving healthcare regulations. This article will help oncology practices make an informed decision about the partner that best fits your practice’s needs.
1. Nexus io
Nexus io is a Phoenix, AZ based medical billing company, started in 2025.Nexus io is providing oncology medical billing services that ensures claims are accurately submitted, prior authorizations are obtained, and that accurate coding is employed in compliance with CPT and ICD-10 rules. Number one providers of chemotherapy, radiation, infusion, and oncology cancer billing are the Nexus io.
Utilizing a 98% collection rate and advancing in the effectiveness of collection of accounts receivable, they come in and get the job done manually to make surgical cancer intervention easy to access by forwarding exactly long-neglected dollars by insurance companies to the clinics who need them to make cancer surgeries.
2. Oncology Billing & Consulting
Oncology Billing & Consulting Firm, LLC (OBCF) was started in 2003 and is located in Clinton, NJ. They provide medical billing services for Hematology and Oncology practices. OBCF is certified by the NJ Dept. of Banking and Insurance and follows all HIPAA rules.
They have a 95–100% collection rate, 18–28 days DSO, a 100% client retention rate, and a 5-star Google review. Their skilled team and advanced technology help with billing, revenue cycle management, appeals, audits, insurance checks, and office support, making sure practices get the reimbursement they deserve.
3. Oncentric
Oncentric, based in New York, NY, provides Oncology Revenue Cycle Management (RCM) services to help cancer practices manage billing and payments more easily. The company has a 5-star rating on Google with 2 reviews.
Using AI and Robotic Process Automation (RPA), Oncentric reduces errors, fixes coding problems, improves clean claims, and speeds up reimbursements. Their expert team creates custom reports to track financial health, making billing more accurate and efficient. This allows oncology practices to save time and increase revenue.
4. PCH Health
PCH Health, a Texan medical institution, with over 30 years of experience combined and 3,000 specialists in their payroll is known for delivering the top-notch oncology billing solutions. They offer oncology medical billing service to the cancer departments to take care of the registration, patient insurance, coding, and submission bills, as well as the denial follow-up.
They are also effective in the billing of cancer treatment such as infusions, radiations and chemotherapy. Comfortably operating with an exceptional 98% of clean claims and a denial rate of less than 6%, they ensure that claims are processed and charges are recouped as soon as possible, unlike most other billing companies.
5. Practolytics
Practolytics, started in 2000 in Columbia, South Carolina, is a top company for Oncology Billing and Revenue Cycle Management. They help cancer care providers focus on patients by handling coding, authorizations, claims, and follow-ups. They work with over 1,400 providers in 31 states, processing more than 5 million claims every year across 28+ specialties.
Their services reduce denials by up to 22% and increase revenue by up to 27%. Fully HIPAA-compliant, Practolytics offers easy-to-use tracking, audits, and expert coding support. ZoomInfo reports their yearly revenue as $19.5 million, showing their strong role in oncology billing.
6. Plutus Health
Plutus Health, started in 2008 in Dallas, TX, is a leading company for oncology billing and coding. They have over 1,100 trained billers and coders and earn $19.5 million in revenue as per Zoominfo.
Their billing services help cancer clinics work faster and smarter, with an average turnaround time of 48 hours, 95% clean claims, 35% higher patient collections, 98% of contracted value collected, less than 5% denials, and 25 A/R days. They handle payment posting, copay help, order entry, and drug billing for all types of oncology.
7. Oncology Convergence, Inc
Oncology Convergence, Inc was started in 2006 and is based in Centennial, Colorado. Making reference to data provided by Zoominfo, this company has an annual turnover of $25.8 million. The company specializes in medical oncology billing and coding for both hospital and independent cancer practices.
The company’s team takes away the billing, coding, claims, and even practice administrative burden, which enables the doctors to solely focus on the patients. Patient-focus, timely, and accurate billing, patient appeals, with practice management is also offered by the company. With the help of Oncology Convergence, one can expect easy and remote support and onboarding, which is doable and being planned for cancer practices all over the United States.
8. Everest A/R Management Group Inc
Everest A/R Management Group Inc, founded in 2001 and based in Gainesville, Florida, delivers expert oncology billing and revenue cycle management services. With a 5-star Google rating from 18 reviews and around $5 million in revenue according to Zoominfo, they focus on maximizing returns while enhancing patient experience.
Their skilled team handles medical, surgical, radiation, gynecologic, and pediatric oncology billing with up-to-date knowledge of coding, compliance, and insurance protocols, ensuring accurate, efficient, and profitable billing solutions tailored to oncology practices.
9. iRCM
iRCM, established in 2013 and based in Brooklyn, New York, provides efficient oncology billing and coding services designed for financial precision and practice success. Boasting a 5-star Google Business Profile with 183 reviews, around $5 million in revenue according to Zoominfo, a 99% claim success rate, a 2.9% monthly earnings fee, and 100% effective denial prevention, iRCM delivers zero-cost practice audits.
Their HIPAA-compliant, automated solutions tackle complex coding, compliance, and denial management across medical, surgical, radiation, pediatric, gynecologic, and urologic oncology, helping practices optimize revenue while allowing oncologists to focus on patient care.
10. Medico Tech LLC
Medico Tech LLC, founded in 2023 in St. Petersburg, Florida, helps cancer care providers focus on what really matters to the patients. They take care of all the tricky billing for treatments like chemotherapy and radiation, making sure everything is accurate and secure.
Their team handles denied claims, patient records, insurance, and provider credentialing, so doctors don’t have to worry. With a 92% first-time claim approval rate, they save time and cut costs. They also provide clear reports and support around the clock, letting providers focus on caring for people, not paperwork.
Things Oncology Practices Must Consider Before Choosing the Right Oncology Billing Company
We are providing some advanced tips that oncology practices should consider when choosing a billing company:
1. Expertise in Oncology Billing
Billing for oncology services comes with a level of complexity that is not usually seen in the medical industry due to the unique treatment services that are provided, such as radiation therapy, chemotherapy, and immunotherapy. The practice of oncology services has important merits that cannot be overlooked.
It assists the company to have reasonable reimbursement, and the medical practice is embracing the right codes: HCPCS, ICD-10, and CPT. Proper coding ensures appropriate billing and maximization of returns. Outsourcing cancer care allows cancer doctors and surgeons to concentrate on patients with little to no errors.
2. Compliance and Data Security
Protecting patient privacy and following rules is very important. The billing company must follow HIPAA laws and keep all patient information safe. They should also handle credentialing for various insurance providers and maintain secure, organized records. A trustworthy company will be prepared for audits and ensure your practice stays fully compliant.
3. Claim Accuracy and Denial Management
If recorded incompletely or coded wrongly, claims do have a high denial rate. Outsourcing to a suitable billing company will have a great impact as the claims should be 100% accurate.
Outsourcing parties should have a systematic process to track, manage, and quickly resolve any denied claims, thus eradicating payment delays and proffering an assured cash flow for your practice.
4. Technology and Reporting Capabilities
Contemporary cancer treatment and billing practices use modern software to take out the fluff. An ideal billing partner must offer all the benefits of electronic health records, account payable and, collections in real-time. Detailed billing reports help medical facilities to track their earning, detect the inconsistencies and make worthwhile decisions to cut down efficiency of the facilities.
5. Customer Support and Communication
Reliable support is key to a smooth billing process. Your billing company should be available to answer questions, resolve issues, and guide your team whenever needed. Clear communication builds trust and ensures that both your staff and patients experience fewer delays and complications. 24/7 support can make a big difference, especially when urgent billing issues arise.
Bottom Line
Choosing the right oncology billing company can completely transform how smoothly your practice runs. If you select a partner based on the tips above expertise in oncology billing, compliance and security, accurate claim management, advanced technology, and strong customer support you will gain faster reimbursements, fewer denials, better compliance, and a more stable cash flow.
To save you time and effort, we have already shortlisted the top oncology billing companies in the USA. We created this list after looking closely at each company’s experience, client feedback, proven results, and overall reputation. By choosing one of these trusted providers, you can focus on giving the best care to your patients while they handle the billing work for you.
